Medical Video: Thiamphenicol


What is the drug for thiamphenicol?

Thiamphenicol is a drug for treating bacterial infections. Thiamphenicol is a class of antibiotic drugs used to treat typhoid fever (typhoid), paratyphoid fever, infection Salmonella sp, influenza, meningitis, and pneumonia. This drug is also useful for treating infections in reproductive organs such as gonorrhea, chlamydia, and so on.

The way the antibiotic thiamphenicol works is to stop the growth of bacteria and prevent the spread of it so that it does not move to other parts of the body. Accidentally taking antibiotics when not needed will make your body more susceptible to infection later on. So, use this medicine as directed by your doctor.

The dose of thiamphenicol and the side effects of thiamphenicol will be explained further below.

How do you use thiamphenicol?

Thiamphenicol is a hard drug that must use a doctor's prescription. Therefore, always follow the rules given by your doctor or pharmacist before starting taking this drug.

Make sure you read the drug guide printed on the packaging label or the Patient Information Brochure provided by the pharmacy, if available, before you get this medicine or every time you buy it again. If you have questions, consult your doctor or pharmacist.

In general, some rules that you should know before taking thiamphenicol antibiotics are:

  • Thiamphenicol is taken usually once or twice a day, or as a doctor recommends.
  • You can take this medicine together at meal or after meals. Drink plenty of water when using this medication, unless the doctor says otherwise.
  • Thiamphenicol is the drug that works best when the amount in your body stays at the same level. Therefore, always make sure the consumption time between one dose of the drug and the next dose is the same. In order not to forget, you can take this medicine at the same time to optimize treatment.
  • Do not grind, chew, or cut the drug into parts unless the doctor recommends it.
  • The duration of treatment and the dose of thiamphenicol are based on medical conditions and response to treatment.
  • Do not double the dose of thiamphenicol if you are late or forget to consume it because it can trigger a disorder in the body.
  • If you forget to take this medicine, drink it immediately if the distance with the next consumption is not too close. But if the next consumption distance is close, ignore it and do not double the dose of thiamphenicol.
  • Continue treatment until the drug runs out even if symptoms disappear after a few days. Stopping treatment too quickly allows the bacteria to continue to grow, which results in the reappearance of the infection.
  • Tell your doctor if your condition does not change, gets worse, or if you experience new symptoms. If you feel you might have a serious medical problem, get medical attention immediately.

How to store thiamphenicol medicine

Thiamphenicol is one medicine that must be stored at room temperature. Keep the drug away from direct sunlight and damp places. Do not store in the bathroom. Don't freeze it.

Other brands of this drug may have different storage rules. Pay attention to the storage instructions on the product packaging or ask your pharmacist. Keep all medicines out of reach of children and pets.

Do not water drugs into the toilet or into the drain unless instructed. Discard this product if the validity period has expired or if it is no longer needed. Consult your local pharmacist or waste disposal agency on how to dispose of your product.


The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

How many doses of thiamphenicol for adults?

To treat sexually transmitted infections susceptible, doses of thiamphenicol are:

1.5 grams per day divided into several doses according to the doctor's recommendations. The maximum dose is 3 grams per day for severe infections.

To treat gonorrhea, the dose of thiamphenicol is:

  • 2.5 grams per day for 1-2 days


  • 2.5 grams on the first day followed by 2 grams per day for the next 4 days

How many doses of thiamphenicol for children?

For susceptible infections, the dose of thiampohenicol is:

  • 30-100 mg / kg body weight / day

In doses is thiamphenicol drug available?

Thiamphenicol is available in the form and strength of the following dosages:

  • Capsules 250 mg and 500 mg
  • 1 gram tablet
  • Dissolved drug (powder)

Overall the administration of the dose of thiamphenicol will be adjusted for age, disease severity, patient health condition, and body response to the drug.

There may be several doses of thiamphenicol that are not mentioned above. If you are in doubt about the dosage of this drug, then please consult a doctor for more information. Your doctor may give you a dose of the drug that suits your condition.

Side effects

What side effects can be experienced due to the use of the drug thiamphenicol?

Thiamphenicol's side effects are mild, such as:

  • Allergic reactions.
  • Nausea, vomiting, abdominal pain, mild diarrhea.
  • Stiff muscles.
  • Joint pain.
  • Feelings of anxiety or hyperactivity.
  • Unusual or unpleasant taste in the mouth.
  • Mild itching or skin rash.
  • Itching in the vagina or discharge from the vagina.

Contact your doctor immediately if you experience serious side effects of lhiamphenicol drugs, such as:

  • Diarrhea in the form of liquid or blood.
  • Fever, chills, pain, flu symptoms.
  • Unusual bleeding or bruising (on the nose, mouth, vagina or rectum), purple or red spots under the skin.
  • Seizures.
  • Pale or yellowing skin.
  • Dark urine.
  • Eye nerve inflammation.
  • Gray baby syndrome in infants.
  • Confusion or fatigue.
  • Fever, swollen glands, rashes and itching, joint pain, or general pain.
  • Increased thirst, loss of appetite, swelling, increased weight, difficulty breathing, less water than usual or not at all.
  • Severe allergic reactions such as swelling of the face or tongue, burning eyes, pain in the skin, followed by a red or purple rash that spreads (especially to the face or upper body) and blisters and flakes.

Side effects may be different for each patient thiamphenicol. So, not everyone experiences the side effects of thiamphenicol. Not everyone experiences the side effects of upper thiamphenicodil.

There may be some side effects of thiamphenicol which are not mentioned above. If you have concerns about certain side effects, consult your doctor or pharmacist

Prevention & Warning

What should be known before using the drug thiamphenicol?

Before using the drug thiamphenicol, it is important for you to consider all the benefits and risks of this drug. Because the drug Thiamphenicol should not be used carelessly. Some of the important things to know before using clindamycin drugs are:


Tell your doctor that you have experienced an allergic reaction or unusual symptoms from using this drug or other drugs. Also tell a health care professional if you have other types of allergies, such as food, coloring, preservatives or animals. For non-prescription drugs, read labels or pack drugs carefully.


Research on this drug is only done in adults, and there is no specific information comparing the benefits of this drug for children up to 12 years of age with benefits for other age groups. Always consult the safety of this drug if it is used for children.


Many drugs have not been studied especially for the elderly. So, it is not clear whether or not this drug is safe when consumed by the elderly. Although there is no specific information that compares the benefits of this drug to elderly people with other age groups, this drug is not expected to cause different side effects for the elderly and for young people.

Pregnancy and breastfeeding

When you are planning to become pregnant or breastfeeding, you should only take medication based on your doctor's recommendation.

Other drugs that you are taking

It is possible if this drug can interact with other drugs that you are taking. This drug interaction can occur in prescription, non-prescription, and herbal medicines. So, always consult a doctor first before using this medicine.

There may be other things not mentioned above. If there are other questions, then please consult a doctor for more information. The doctor may provide more complete information, including the dosage, safety, and interaction of this drug. Take a good look at all the information explained by the doctor so that the treatment you perform runs optimally.

Is thiamphenicol medicine safe for pregnant and lactating women?

There is no adequate research on the risks of using this drug in pregnant or lactating women. Always consult your doctor to consider the potential benefits and risks before using this drug.

This drug is included in the risk of category B pregnancy according to the Food and Drug Administration (FDA) in the United States, which is equivalent to the POM Agency in Indonesia.

Here's the FDA's pregnancy risk category reference:

  • A = No risk,
  • B = No risk in some studies,
  • C = Probably risky,
  • D = There is positive evidence of risk,
  • X = Contraindications,
  • N = Unknown

It is not known whether this drug can be absorbed by breast milk or can harm the baby. Do not use this medicine without telling your doctor if you are breastfeeding.

The point is, don't forget to always consult your doctor before taking antibiotics thiamphenicol if you are pregnant, planning to become pregnant, or even breastfeeding.


What medicines can interact with thiamphenicol?

Thiamphenicol can interact with other drugs that you use today by changing how the drug works or increasing the risk of serious side effects.

To avoid possible drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, non-prescription drugs, and herbal products) and notify your doctor and pharmacist.

The use of the drug thiamphenicol can with the drugs attached below are generally not recommended, but may be needed in some cases. If both drugs are prescribed together, your doctor may change the dose or how often you use one or the other.

  • Tolbutamide
  • Phenytoin
  • Dicoumarol
  • Other drugs that are metabolized in the liver

There may be some medicines not mentioned above. If you are in doubt about this drug interaction with other drugs that you are taking, then please consult a doctor for more information. Your doctor may prescribe other drugs that are appropriate for your condition.

For safety reasons, never even try to start, stop, or change the dose of any drug without your doctor's approval.

Can food or alcohol interact with drugs?

Certain drugs cannot be used at meals or when eating certain foods because drug interactions can occur. Eating alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss using your medicine with food, alcohol, or tobacco with your doctor.

Are there diseases that can interact with the drug thiamphenicol?

Thiamphenicol may interact with your health condition. This interaction can worsen your health condition or even change the way the drug works. Therefore, it is important for you to always tell your doctor or pharmacist about the health conditions that you currently have. Some health conditions that may interact with thiamphenicol drugs are:

  • Hypersensitivity.
  • Pre-existing bone marrow depression.
  • Impaired kidney function.
  • Atopic syndrome.
  • Liver disfunction.
  • Meningitis.

There may be some health conditions not mentioned above. If you are in doubt about your health condition, then don't hesitate to consult a doctor. Your doctor may prescribe other drugs that are appropriate for your condition.


What should I do in an emergency or overdose?

In emergency cases or overdoses, contact a local emergency service provider (118) or immediately to the nearest hospital emergency unit.

Some of the most common symptoms of drug overdose include:

  • Nausea.
  • Gag.
  • Dizzy.
  • Lost balance.
  • Numbness and tingling.
  • Seizures.

There may be some signs and symptoms of drug overdose not mentioned above. If you are in doubt about this, please consult a doctor for more information.

What should I do if I skip one dose?

If you forget about one dose of this drug, drink it as soon as possible. However, if it is nearing the time of the next dose, skip the forgotten dose and return to the usual dosage schedule. Don't double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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