Contents:
- Medical Video: Treatments for Type 1 Diabetes | Nucleus Health
- How it works amylin analog
- Which must be considered
Medical Video: Treatments for Type 1 Diabetes | Nucleus Health
Amylin analog, or agonist, is an injection drug used for the treatment of type 1 diabetes and type 2 diabetes. Amylin is an amino acid polypeptide hormone 37 secreted with insulin from pancreatic beta cells. In the case of diabetes, lack of insulin also means lack of amylin. Amylin helps insulin control postprandial glucose, inhibits glucagon secretion, delays the stomach stomach, gives a full signal, and also suppresses appetite.
This substance is given before meals, and will work like the amylin hormone.
Amylin has a number of benefits in reducing weight and reducing blood glucose levels.
Pramlintida is a drug in the analog amylin group.
How it works amylin analog
Amylin is an amino acid polypeptide hormone produced by the pancreas and released together with insulin, but in much smaller amounts (about 1% compared to insulin).
This hormone helps insulin control glucose levels after eating. It works by inhibiting the release of glucagon when eating, slowing down the digestive process of food, thus preventing the stomach from quickly emptying and holding back appetite.
Amylin agonists have functions similar to the amylin hormone and have been shown to significantly reduce weight, long-term average blood glucose (HbA1c), and even insulin doses for diabetics who use insulin injections.
What are the side effects of using amylin analog?
You can experience certain side effects (such as nausea, vomiting and low blood sugar) when you start using analog amylin. Therefore the initial dose should be a little to allow the body to adjust to new drugs.
Common side effects caused by the use of amylin analog include:
- Nausea
- Hypoglycemia (blood glucose is too low) if taken with insulin
- Gag
- Headache
- Stomach ache
- Weight loss
- Fatigue
Which must be considered
By inhibiting the release of glucagon, amylin analog can prevent the body from increasing blood glucose levels when not needed, for example the response to food.
However, the disadvantage of using Amylin is that it can also inhibit glucagon release to increase blood glucose levels when blood sugar levels are low which can be a problem for the body.
