Contents:
- Medical Video: LIVER FUNCTION TESTING! - AST, ALT, and ALP- Is your liver in SERIOUS TROUBLE?
- What is SGPT and SGOT?
- Why do doctors recommend checking SGPT and SPOT?
- What must be prepared before checking SGPT and SGOT?
- What medicines can affect the SGPT and SGOT test results?
- Painkillers, such as:
- Anti-seizure medication:
- Antibiotics:
- Cholesterol-lowering drugs:
- Heart and blood vessel medications:
- Get to know the procedure for checking SGPT and SGOT
Medical Video: LIVER FUNCTION TESTING! - AST, ALT, and ALP- Is your liver in SERIOUS TROUBLE?
There are various types of health checks that are often done when you are suspected of having a certain disease. One of them is checking levels of SGPT (Serum Glutamic Oxaloacetic Transaminase) and SGOT (Serum Glutamoc Oxaloecetic Transaminase). Usually, people who experience symptoms of hepatitis B or C are advised to ascertain their SGOT and SGPT conditions. Well, what is the mechanism of the test? Does something have to be prepared? Are the results of SGPT and SGOT only for people who are hepatitis? See the explanation below.
What is SGPT and SGOT?
SGPT and SGOT are the ingredients of enzymes produced in the body. SGPT can also be called AST (aminotransferase), while SGOT can be called ALT (alanine aminotransferase) in the results of checking your lab.
Both of these enzymes are responsible for helping metabolic processes in the body. The difference is that SGPT levels are generally found in the liver, while SGOT levels other than those found in the liver are also found in the brain, muscles, heart, pancreas, and kidneys.
If the levels of these two enzymes are high, further action is needed.
Why do doctors recommend checking SGPT and SPOT?
This test is done to help diagnose whether a person has liver dysfunction or not. Your doctor or health worker will ask for this test if you find some symptoms such as:
- Jaundice (jaundice)
- Dark urine color
- Nausea and vomiting
- Pain in the abdomen, precisely at the location of the liver
Allegedly, the person who has these symptoms has liver disease so it must be examined further from this SGPT value.
However, not always checking SGPT is done because of the symptoms alone. The SGPT test will also be done usually for:
- Evaluate the development of liver disease experienced such as hepatitis, cirrhosis and other liver disorders.
- See if the patient needs treatment or not. There are a number of cases of disease whose effects of treatment trigger liver damage. For example, cases of tuberculosis (TB). Some body TB patients are not strong with side effects from these drugs that are hard on the liver. Furthermore, TB patients who are suspected of experiencing damage in the liver will begin to be given treatment for their hearts so as not to get worse.
- Evaluate how well a health care has been given.
For SGOT, it is usually also done to see conditions for liver disease such as hepatitis. Usually SGOT will be measured with SGPT. Because SGOT is present in several places in the body, SGOT does not only indicate damage in the liver. SGOT can also indicate damage to other body tissues that contain this enzyme.
What must be prepared before checking SGPT and SGOT?
Both of these tests do not require special steps or preparations before they are implemented. However, you should tell your doctor what medicines are being consumed. This is to avoid inaccurate test results.
Some drugs can affect this outcome. The doctor will usually stop using the drug that is thought to affect the results of this test at some time before the test.
What medicines can affect the SGPT and SGOT test results?
There are several drugs that are thought to affect the results of SGPT and SGOT levels that are original in the body. Well, for that there are some medicines that need to be stopped before the test so that the results show the right numbers.
The value of SGPT or SGOT can usually return to its original level after stopping use of the drug in a few weeks or several months.
Therefore, the doctor must know what drugs are being consumed before carrying out the SGPT and SGOT levels. One of them is a tricyclic type antidepressant drug.
In addition, these drugs can also affect results:
Painkillers, such as:
- Aspirin
- Acetaminophen
- Ibuprofen
- Naproxen
- Disclofenac
- Phenylbutazone
Anti-seizure medication:
- Phenytoin
- Valporic acid
- Carbamazepine
Antibiotics:
- Sulfonamides
- Isoniazid
- Sulfamethoxazole
- Trimethoprim
- Nitrofurantoin
- Fluconazole
Cholesterol-lowering drugs:
- Lovastatin
- Pravastatin
- Atrovastatin
- Fluvastatin
- Ssimvastatins
- Rosuvastin
Heart and blood vessel medications:
- Qinidine
- Hydralazine
- Amiodarone
Get to know the procedure for checking SGPT and SGOT
SGPT and SGOT examination is done by assessing the levels in the blood. The health worker will take a blood sample in the hand. Precisely in a vein called a vein. The following are the steps:
- Before injecting the needle into the patient's hand, the clerk will usually clean the area of the skin to be pierced with a needle using cotton and alcohol.
- Next, to easily find your vein, the clerk will attach an elastic bracelet to the upper arm. This bracelet will stop the blood flow so that it makes the vein more visible.
- When a vein has been found, the health worker will inject a needle into your vein. This can cause a sensation such as being pinched small or stung with a short time.
- Blood is flowed into a tube to hold blood. Blood can be drained into the tube because the needle is connected by a small tube which is a tube to the tube.
- If blood is enough, the injection will be released. Likewise with the elastic bracelet.
- The clerk then puts the cotton in the place that was injected.
- Blood samples are taken to the laboratory to analyze how much SGPT levels are and what levels of SGOT are in the blood. Next, the doctor will explain the results to you and make a diagnosis.
