Contents:
Medical Video: Hemostasis: Lesson 4 - Tests (INR, PTT, platelets, fibrinogen, D-dimer)
Definition
What is the concentration of coagulation factor?
Coagulation factor concentration tests are performed to help doctors evaluate the ability and duration of the blood clotting process in the body. This coagulation test is done to prevent excessive bleeding when you are injured. However, if a clot in a normal vein is found, it is very dangerous because it can clog the blood flow to the heart, lungs, and brain, then it can cause a heart attack or stroke.
By doing this test, your doctor can detect how much risk of bleeding will occur to you if you are injured, or detect whether you have a heart attack / stroke or not.
When should I undergo coagulation factor concentrations?
The doctor will do this test if:
- the doctor wants to know the cause of the bleeding in your body
- when you are about to take warfarin, this test is useful for determining the dose of warfarin you should consume
- performed to detect hereditary diseases such as hemophilia
- check if you lack vitamin K. Vitamin K is an important substance in the blood clotting process
- test whether you are ready for surgery or not
- check whether liver function works properly, because the liver produces important substances in the blood clotting process
- check whether with bleeding that occurs in you, you can have a heart attack or stroke
Prevention & warning
What should I know before undergoing coagulation factor concentration?
Here are some factors that influence your test results:
- various proteins that are sensitive to heat, the concentration factor will decrease if the sample is stored at room temperature
- pregnancy or taking oral birth control pills, the concentration factor is likely to increase, especially factors VII and IX
- there are many other blood clotting factors that can increase if the body is in a stressful state or your body is inflamed.
It is important for you to know the warnings and precautions before carrying out this operation. If you have questions, consult your doctor for further information and instructions.
Process
What should I do before undergoing coagulation factor concentration?
You do not have to make special preparations before doing this test. There are several drugs that can change results, so you should tell your doctor about any medications you are taking (with prescription or over-the-counter), including supplements and vitamins.
You should use short sleeves to make it easier for nurses to take your blood.
What is the process of coagulation factor concentration?
The medical personnel who are in charge of taking your blood will take the following steps:
- wrap an elastic belt around your upper arm to stop the blood flow. This makes the blood vessels under the bond enlarge making it easier to inject needles into the vessels
- clean the part to be injected with alcohol
- inject a needle into a vein. More than one needle may be needed.
- attach the tube to the syringe to fill it with blood
- remove the ties from your arms when taking blood is enough
- attach gauze or cotton to the injected part, after the injection is finished
- put pressure on the part and then put on a bandage
What should I do after undergoing coagulation factor concentrations?
Your doctor or nurse will take your blood to test cholesterol and triglyceride levels. The pain you feel usually depends on the ability of the nurse, the condition of the veins, and the sensitivity of your skin. After blood is taken, the injection syringe should be bandaged and pressed gently to stop the bleeding.
If you have questions relating to the process of this test, consult your doctor for a better understanding.
Explanation of Test Results
What do the test results mean?
Normal results:
| Factor | Normal range (% concentration) |
| II | 80-120 |
| V | 50-150 |
| VII | 65-140 |
| VIII | 55-145 |
| IX | 60-140 |
| X | 45-155 |
| XI | 65-135 |
| XII | 50-150 |
Abnormal results:
| Factor | High (exceeding normal) |
| I (Fibrinogen) | Acute inflammation Injury Heart disease Smoke |
| II (Prothrombin) | There is no common disease |
| V (Procaccelerin) | There is no common disease |
| VII (Proconvertin [stable factor]) | There is no common disease |
| VIII (anti-clogging factor) | Acute inflammation Trauma / Stress Pregnant Using PK pills |
| von Willebrand | There is no common disease |
| IX (Christmas factor) | There is no common disease |
| X (Stuart factor) | There is no common disease |
| XII (Hageman factor) | There is no common disease |
DIC: Disseminated intravascular coagulation
Depending on the laboratory of your choice, the normal range of these tests can vary. Discuss the questions you have about the results of your health test with your doctor.
Hello Health Group does not provide medical advice, diagnosis or treatment.
