Contents:
- Medical Video: How To Treat Insomnia Naturally Without Medication Fix Sleeping Problems | Best Way To Sleep Better
- Sleep deprivation makes pain medication unable to function
- Caffeine and modafinil were able to relieve pain
Medical Video: How To Treat Insomnia Naturally Without Medication Fix Sleeping Problems | Best Way To Sleep Better
Painkillers are one of the many types of drugs that are often used without a doctor's prescription. This drug is often consumed when a person has mild headaches or menstrual cramps.Well, if you are one of the people who often take painkillers, a recent study reveals an unexpected relationship between lack of sleep and sensitivity to pain. This finding may have significant implications for the use of painkillers. See the full explanation in this article.
Sleep deprivation makes pain medication unable to function
In a study published in the journal Nature Medicine, the researchers conducted the study by giving toys and various activities to experimental mice so that they remained awake. During this period of awake, the researchers monitored drowsiness, stress levels, and sensitivity to pain. This is done to imitate the condition of people who lack sleep. After five days the mice were made sleep deprived, it is known that these mice turned out to be more sensitive to pain.
Then the researchers gave painkillers such as ibuprofen and morphine to see if the two drugs inhibited the extra pain caused by lack of sleep. The result was that ibuprofen did not help reduce pain. In addition, morphine is often used to relieve severe pain, it is also not very effective.
Well, this raises the assumption that people who use similar drugs to relieve pain but on the other hand they also lack sleep, may need to increase the dose so that the effect is felt. However, this raises concerns that will occur from side effects if the drug is used at high doses.
Caffeine and modafinil were able to relieve pain
When drowsy and lacking in enthusiasm, usually a cup of coffee can help to make us "wake up" again. But besides keeping us awake, coffee may have other uses too. Based on these studies, caffeine is believed to help relieve pain.
But when the researchers gave drugs to keep them awake, like caffeine and modafinil, it turned out that they could actually block the pain triggered by sleep deprivation. Caffeine and modafinil trigger dopamine production in the brain, which may have a role to eliminate pain. Even so, how caffeine and modafinil can work to relieve pain is still unclear.
That is why, from the study it was concluded that adequate sleep and consuming substances that keep us awake, such as coffee, could be an effective strategy for relieving chronic pain. But further research is needed on humans to determine how long sleep is needed to reduce pain and whether caffeine can help eliminate it.
