Benefits of Red Orange & Grapes for People with Diabetes and Heart

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A mixture of two ingredients which are found in oranges and red wine has recently been found to help people with type 2 diabetes, obesity, and heart disease. Research conducted at University of WarwickThe British hope that this discovery can be developed into a new treatment for patients. Professor Thornalley, leader of the study, stated that this discovery could have an important influence on the ability of the current medical team to treat these diseases.

What content in oranges and red wine can help people with diabetes, obesity, and heart disease?

In red wine, there is a component called trans-resveratrol (tRES). Whereas in oranges, there is a component called hesperetin (HESP). These two components have never stood together. However, if these two components are mixed in certain doses for the needs of the drug, then these two components will work well together to reduce blood sugar levels, improve insulin work, and improve health in the heart arteries.

tRES and HESP will work to increase the protein in the body called glyoxalase 1 (Glo1). This Glo1 protein functions to neutralize the components in the body called methylglyoxal (MG). MG itself is a destructive component of taking sugar in the body. High MG levels in the body, accompanied by a diet with high carbohydrates, will make insulin in the body become resistant, which results in type 2 diabetes, damage to blood vessels, and loss of the body's ability to control cholesterol which increases the risk of heart disease.

Neutralizing MG by increasing Glo1 can improve health for obese people, while helping patients with diabetes and patients who have a high risk of heart disease. In practice, it has been proven that neutralizing MG can improve health for sufferers of obesity, type 1 diabetes, and type 2 diabetes.

Just eating fruit is not enough

The components of tRES and HESP can indeed be obtained from fruits naturally. However, the amount needed to improve health will not be enough to just eat lots of these fruits. These two components will be bred in the laboratory. Then, in certain doses, these two components will be formulated in the form of tablets or capsules, so that both components can work to improve the quality of life for people with obesity, diabetes, and the risk of heart disease.

The trial process that has been successfully carried out

Scientists have tried this treatment. 32 people aged 18-80 years who are obese (or have Body Mass Index between 25-40). These people are given capsules that have been formulated with tRES and HESP once a day for eight weeks. They were also asked to eat with their diet as usual, but the food they ate was observed by filling out the questionnaire. In addition, they were also asked not to change their physical activity routine. After that, changes in the levels of sugar in their bodies were measured by testing blood samples, the health of their heart arteries was measured by artery wall flexibility, and other tests using blood samples.

The results are very satisfying. The team found that after eating the capsules, obese people who took part in the trial had increased Glo1 in their bodies. As a result, the levels of sugar in their bodies decrease, the amount of insulin that works in their bodies increases, the function of their heart arteries increases, and inflammation in their blood vessels decreases. No failure was found, aka death, in this experiment. These findings also prove that Glo1 deficiency is a trigger for health problems such as obesity, diabetes and heart disease.

However, the scientists acknowledged that the combination of tRES and HESP they gave to the trial participants was rather too much. Therefore, they want to further formulate the most effective combination of tRES and HESP to increase Glo1 protein.

This drug is in the process of being produced for the public

From the results of this impressive experiment, currently a team of scientists is collaborating to bring these drugs for sale commercially. With the discovery of this drug, the health of people with obesity, diabetes, and heart disease can be better.

However, keep in mind, too, if in the future this drug reaches your hands, it doesn't mean that after you take this medicine then you can live as you wish. You still have to maintain your physical activity, your diet, and your other lifestyle to support you to stay healthy and avoid obesity, diabetes and heart disease.

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Benefits of Red Orange & Grapes for People with Diabetes and Heart
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