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Medical Video: 10 Facts About VIAGRA That Will Shock You | LIST KING
Since it was first introduced in March 1998, there are no other therapies for managing erectile dysfunction, which have gained widespread public recognition, besides Viagra.
Viagra, a drug that has the generic name sildenafil, helps increase blood flow to the penis so that the owner can maintain an erection.
But did you know that this popular drug was created accidentally? Initially, sildenafil was in the stage of testing drugs to cure angina (seated wind) - a condition of narrowing of the arteries in charge of supplying the heart with blood - thanks to the effect that relaxes blood vessels. In the process, finally the blue pill that we know so far has been inaugurated as an anti-impotence drug.
To understand more about how Viagra works, it's good to first understand how you can (and don't) get an erection.
The penis mechanism reaches erection
Try moving one of your limbs - blinking, for example, or sticking out your tongue. When you move almost every limb, you do it with muscles. You think about moving it, the muscles in question will contract, and the limbs you need will move. Unlike the penis. There is no muscle contraction involved in making the penis erect. To make your genitalia "stand up", the penis uses pressure.
In short, to get an erection, you need three things: healthy blood flow, a healthy nervous system, and sexual arousal (libido). If the flow of blood that leads to the penis does not work properly, for example if the entrance of blood (arteries) is too narrow or if blood flows too fast through the exit gate (vein), you may be able to have difficulty achieving or maintaining an erection. Blood flow problems, in addition to other medical and psychological conditions, are a major cause of erectile dysfunction (impotence).
How does the viagra drug work to overcome impotence?
Viagra works by inhibiting PDE-5, an enzyme produced after sex is over and makes the penis go back 'wilted'. This makes the muscles in the penis more likely to relax and allow blood to flow in, causing erections.
The sildenafil citrate contained in viagra, acts as the main active component in charge of plowing the performance of PDE-5 and deactivating the enzyme. When a man consumes a blue pill, sildenafil citrate flows throughout the body, but only affects the PDE-5 enzyme in the penis.
Once PDE-5 is blocked, compounds called cGMP can gather in the penis and increase blood flow to the penis, without affecting other body parts (Note: PDE has many types, but PDE-5 is the most found enzyme in the penis). That is, the greater the amount of cGMP, the more blood flowing. The more rapid blood flow to your penis, the greater the level of erection.
It is important to understand that taking Viagra tablets alone will not cause erections. Viagra must be taken in combination with several forms of sexual stimulation (visual, touch, or both) so that erections can occur. Without sexual stimulation, Viagra will not have any effect.
Viagra works well if taken 30-60 minutes before sexual activity.
How long can Viagra maintain an erection?
Only 1 tablet must be used in one day, and on an empty stomach. Increasing the dosage of Viagra beyond the recommended amount will not improve response, and will only increase the risk of dangerous side effects.
The duration of erection can last after Viagra use varies depending on the user (based on age, diet, alcohol consumption, dosage, health conditions, and drug interactions). But in general, Viagra can maintain an erection for 4-5 hours after use coupled with sexual stimulation.
On the other hand, most men find that this magical blue pill effect will start to fade within 2-3 hours after first consumption.
The drug will remain in the blood for about four hours, and then it will be rinsed clean of your circulatory system by the liver and kidneys.
Those who may or may not take Viagra
In general, Viagra works effectively up to 65-70% in all impotent men.
Keep in mind, these pills may not be strong enough for those who have too much arterial narrowing.
In addition, because Viagra works similar to a drug containing nitrate, it is not recommended for men who take nitrate drugs for heart disease, or those with certain other heart conditions to take Viagra. In some men, this drug causes bad headaches.
